E15-EXPODIET: Exposición alimentaria a contaminantes ambientales

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El grupo de Nutrición, Dieta y Evaluación de Riesgos se centra en la Investigación de la Exposición Alimentaria a Disruptores Endocrinos y su efecto en enfermedades metabólicas como la obesidad.

Líneas de investigación

Estimación de la exposición a disruptores endocrinos en población europea
Estudio del efecto de la exposición a disruptores endocrinos en diferentes enfermedades
Estudio del efecto de la exposición a disruptores endocrinos en la microbiota
Identificación de genes asociados a las enfermedades hormono-dependientes

Palabras clave

Disruptor endocrino, Exposición Alimentaria, Obesidad

LUIS JAVIER MARTINEZ GONZALEZ

ORCID

INMACULADA MOSCOSO RUIZ

VIVIANA RAMIREZ LOPEZ

JORGE MORENO FERNANDEZ

ORCID

SILVIA MARTINEZ DIZ

JAVIER DIAZ CASTRO

ANA LOPEZ MORENO

ORCID

MARIA VEGA ALMAZAN FERNANDEZ DE BOBADILLA

RAQUEL AVILA VILLEGAS

MARIA JESUS ALVAREZ CUBERO

ORCID

ALBERTO ZAFRA GOMEZ

YOLANDA GALVEZ ONTIVEROS

CELIA MONTEAGUDO SANCHEZ

ANA MARIA RIVAS VELASCO

Puche-Juarez, M; Toledano, JM; Moreno-Fernandez, J; Galvez-Ontiveros, Y; Rivas, A; Diaz-Castro, J; Ochoa, JJ

The Role of Endocrine Disrupting Chemicals in Gestation and Pregnancy Outcomes

NUTRIENTS, 2023;

FI:5,9; Q1

Moscoso-Ruiz, I; Gálvez-Ontiveros, Y; Samaniego-Sánchez, C; de Bobadilla, VAF; Monteagudo, C; Zafra-Gómez, A; Rivas, A

Presence of Parabens in Different Children Biological Matrices and Its Relationship with Body Mass Index

NUTRIENTS, 2023;

FI:5,9; Q1

Gálvez-Ontiveros, Y; Moscoso-Ruiz, I; de Bobadilla, VAF; Monteagudo, C; Giménez-Martinez, R; Rodrigo, L; Zafra-Gómez, A; Rivas, A

Levels of Bisphenol A and its analogs in nails, saliva, and urine of children: a case control study

FRONTIERS IN NUTRITION, 2023;

FI:5; Q2

Moscoso-Ruiz, I; Navalón, A; Rivas, A; Zafra-Gómez, A

Presence of parabens in children?s faeces. Optimization and validation of a new analytical method based on the use of ultrasound-assisted extraction and liquid chromatography-tandem mass spectrometry

JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2023;

FI:3,4; Q2

Van Pamel, E; Ruiz-Rodríguez, A; Rivas, A; Aguilera, M

Editorial: Risk of dietary hazardous substances and impact on human microbiota: possible role in several dysbiosis phenotypes, volume II

FRONTIERS IN MICROBIOLOGY, 2023;

FI:5,2; Q2

Moreno-Fernandez, J; Ochoa, JJ; Matallana, CD; Cano, A; Martin-Alvarez, E; Sanchez-Romero, J; Toledano, JM; Puche-Juarez, M; Prados, S; Ruiz-Duran, S; Diaz-Meca, L; Carrillo, MP; Diaz-Castro, J

COVID-19 during Gestation: Maternal Implications of Evoked Oxidative Stress and Iron Metabolism Impairment.

ANTIOXIDANTS, 2022;

FI:7,675; D1

Martin-Way, D; Puche-Sanz, I; Cozar, JM; Zafra-Gomez, A; Gomez-Regalado, MDC; Morales-Alvarez, CM; Hernandez, AF; Martinez-Gonzalez, LJ; Alvarez-Cubero, MJ

Genetic variants of antioxidant enzymes and environmental exposures as molecular biomarkers associated with the risk and aggressiveness of bladder cancer

SCIENCE OF THE TOTAL ENVIRONMENT, 2022;

FI:10,753; D1

Toledano, JM; Moreno-Fernandez, J; Puche-Juarez, M; Ochoa, JJ; Diaz-Castro, J

Implications of Vitamins in COVID-19 Prevention and Treatment through Immunomodulatory and Anti-Oxidative Mechanisms

ANTIOXIDANTS, 2022;

FI:7,675; D1

Ramirez, V; Galvez-Ontiveros, Y; Gonzalez-Domenech, PJ; Baca, MA; Rodrigo, L; Rivas, A

Role of endocrine disrupting chemicals in children’s neurodevelopment

ENVIRONMENTAL RESEARCH, 2022;

FI:8,431; D1

Lopez-Moreno, A; Ruiz-Moreno, A; Pardo-Cacho, J; Cerk, K; Torres-Sanchez, A; Ortiz, P; Ubeda, M; Aguilera, M

Culturing and Molecular Approaches for Identifying Microbiota Taxa Impacting Children’s Obesogenic Phenotypes Related to Xenobiotic Dietary Exposure.

NUTRIENTS, 2022;

FI:6,706; Q1

Monteagudo, C; Robles-Aguilera, V; Salcedo-Bellido, I; Galvez-Ontiveros, Y; Samaniego-Sanchez, C; Aguilera, M; Zafra-Gomez, A; Burgos, MAM; Rivas, A

Dietary exposure to parabens and body mass index in an adolescent Spanish population.

ENVIRONMENTAL RESEARCH, 2021;

FI:6,498; D1

Martin-Pozo, L; Gomez-Regalado, MD; Moscoso-Ruiz, I; Zafra-Gomez, A

Analytical methods for the determination of endocrine disrupting chemicals in cosmetics and personal care products: A review

TALANTA, 2021;

FI:6,057; Q1

Martin-Pozo, L; Gomez-Regalado, MD; Cantarero-Malagon, S; Navalon, A; Zafra-Gomez, A

Determination of ultraviolet filters in human nails using an acid sample digestion followed by ultra-high performance liquid chromatography-mass spectrometry analysis

CHEMOSPHERE, 2021;

FI:7,086; Q1

Torres-Sanchez, A; Pardo-Cacho, J; Lopez-Moreno, A; Ruiz-Moreno, A; Cerk, K; Aguilera, M

Antimicrobial Effects of Potential Probiotics of Bacillus spp. Isolated from Human Microbiota: In Vitro and In Silico Methods

MICROORGANISMS, 2021;

FI:4,128; Q2

Gonzalez, MJL; Botella, CR; Soto, EM; Gaya, MVO; Fernandez, JM; Castro, JD

Body composition, mineral metabolism, and endocrine function of adipose tissue: influence of a nutritional supplement of propolis

NUTRICION HOSPITALARIA, 2021;

FI:1,057; Q4

Martin, J; Hidalgo, F; Alonso, E; Garcia-Corcoles, MT; Vilchez, JL; Zafra-Gomez, A

Assessing bioaccumulation potential of personal care, household and industrial products in a marine echinoderm (Holothuria tubulosa)

SCIENCE OF THE TOTAL ENVIRONMENT, 2020;

FI:6,551; D1

Parra-Luna, M; Martin-Pozo, L; Hidalgo, F; Zafra-Gomez, A

Common sea urchin (Paracentrotus lividus) and sea cucumber of the genus Holothuria as bioindicators of pollution in the study of chemical contaminants in aquatic media. A revision

ECOLOGICAL INDICATORS, 2020;

FI:4,229; Q1

Martin-Pozo, L; Cantarero-Malagon, S; Hidalgo, F; Navalon, A; Zafra-Gomez, A

Determination of endocrine disrupting chemicals in human nails using an alkaline digestion prior to ultra-high performance liquid chromatography-tandem mass spectrometry

TALANTA, 2020;

FI:5,339; Q1

Aguilera, M; Galvez-Ontiveros, Y; Rivas, A

Endobolome, a New Concept for Determining the Influence of Microbiota Disrupting Chemicals (MDC) in Relation to Specific Endocrine Pathogenesis

FRONTIERS IN MICROBIOLOGY, 2020;

FI:4,236; Q1

Galvez-Ontiveros, Y; Paez, S; Monteagudo, C; Rivas, A

Endocrine Disruptors in Food: Impact on Gut Microbiota and Metabolic Diseases

NUTRIENTS, 2020;

FI:4,546; Q1

Andujar, N; Galvez-Ontiveros, Y; Zafra-Gomez, A; Rodrigo, L; Alvarez-Cubero, MJ; Aguilera, M; Monteagudo, C; Rivas, A

Bisphenol A Analogues in Food and Their Hormonal and Obesogenic Effects: A Review

NUTRIENTS, 2019;

FI:4,171; Q1

de la Torre-Robles, A; Monteagudo, C; Mariscal-Arcas, M; Lorenzo-Tovar, ML; Olea-Serrano, F; Rivas, A

Effect of Light Exposure on the Quality and Phenol Content of Commercial Extra Virgin Olive Oil during 12-Month Storage

JOURNAL OF THE AMERICAN OIL CHEMISTS SOCIETY, 2019;

FI:1,72; Q2

Urquiza-Salvat, N; Pascual-Geler, M; Lopez-Guarnido, O; Rodrigo, L; Martinez-Burgos, A; Cozar, JM; Ocana-Peinado, FM; Alvarez-Cubero, MJ; Rivas, A

Adherence to Mediterranean diet and risk of prostate cancer

AGING MALE, 2019;

FI:2,5; Q2

Garcia-Corcoles, MT; Cipa, M; Rodriguez-Gomez, R; Rivas, A; Olea-Serrano, F; Vilchez, JL; Zafra-Gomez, A

Determination of bisphenols with estrogenic activity in plastic packaged baby food samples using solid-liquid extraction and clean-up with dispersive sorbents followed by gas chromatography tandem mass spectrometry analysis

TALANTA, 2018;

FI:4,244; Q1

Melguizo-Rodriguez, L; Manzano-Moreno, FJ; De Luna-Bertos, E; Rivas, A; Ramos-Torrecillas, J; Ruiz, C; Garcia-Martinez, O

Effect of olive oil phenolic compounds on osteoblast differentiation

EUROPEAN JOURNAL OF CLINICAL INVESTIGATION, 2018;

FI:3,086; Q1

Melguizo-Rodriguez, L; Ramos-Torrecillas, J; Manzano-Moreno, FJ; Illescas-Montes, R; Rivas, A; Ruiz, C; De Luna-Bertos, E; Garcia-Martinez, O

Effect of phenolic extracts from different extra-virgin olive oil varieties on osteoblast-like cells

PLOS ONE, 2018;

FI:2,766; Q1

Lopez-Guarnido, O; Urquiza-Salvat, N; Saiz, M; Lozano-Paniagua, D; Rodrigo, L; Pascual-Geler, M; Lorente, JA; Alvarez-Cubero, MJ; Rivas, A

Bioactive compounds of the Mediterranean diet and prostate cancer

AGING MALE, 2018;

FI:2,5; Q2

Scander, H; Monteagudo, C; Nilsen, B; Tellstrom, R; Yngve, A

Beverage consumption patterns and energy contribution from beverages per meal type: results from a national dietary survey in Sweden

PUBLIC HEALTH NUTRITION, 2018;

FI:2,485; Q2

Jimenez, B; Rivas, A; Lorenzo, ML; Sanchez-Ortiz, A

Chemosensory characterization of virgin olive oils obtained from organic and conventional practices during fruit ripening

FLAVOUR AND FRAGRANCE JOURNAL, 2017;

FI:1,644; Q2

Monteagudo, C; Scander, H; Nilsen, B; Yngve, A

Folate intake in a Swedish adult population: Food sources and predictive factors

FOOD & NUTRITION RESEARCH, 2017;

FI:2,039; Q2

Nilsen, BB; Yngve, A; Monteagudo, C; Tellstrom, R; Scander, H; Werner, B

Reported habitual intake of breakfast and selected foods in relation to overweight status among seven- to nine-year-old Swedish children

SCANDINAVIAN JOURNAL OF PUBLIC HEALTH, 2017;

FI:1,339; Q3

Rivas, A; Monteagudo, C; Heras-Gonzalez, L; Mariscal-Arcas, M; Lorenzo-Tovar, ML; Olea-Serrano, F

Association of bisphenol A exposure with dietary quality indices in Spanish schoolchildren

FOOD AND CHEMICAL TOXICOLOGY, 2016;

FI:3,584; D1

Benhammou, S; Heras-Gonzalez, L; Ibanez-Peinado, D; Barcelo, C; Hamdan, M; Rivas, A; Mariscal-Arcas, M; Olea-Serrano, F; Monteagudo, C

Comparison of Mediterranean diet compliance between European and non-European populations in the Mediterranean basin

APPETITE, 2016;

FI:3,125; Q1

Monteagudo, C; Mariscal-Arcas, M; Heras-Gonzalez, L; Ibanez-Peinado, D; Rivas, A; Olea-Serrano, F

Effects of maternal diet and environmental exposure to organochlorine pesticides on newborn weight in Southern Spain

CHEMOSPHERE, 2016;

FI:3,698; Q1

Garcia-Martinez, O; De Luna-Bertos, E; Ramos-Torrecillas, J; Ruiz, C; Milia, E; Lorenzo, ML; Jimenez, B; Sanchez-Ortiz, A; Rivas, A

Phenolic Compounds in Extra Virgin Olive Oil Stimulate Human Osteoblastic Cell Proliferation

PLOS ONE, 2016;

FI:3,057; Q1

Monteagudo, C; Mariscal-Arcas, M; Rivas, A; Lorenzo-Tovar, ML; Tur, JA; Olea-Serrano, F

Proposal of a Mediterranean Diet Serving Score

PLOS ONE, 2015;

FI:3,234; Q1

Palacin-Arce, A; Monteagudo, C; Beas-Jimenez, JD; Olea-Serrano, F; Mariscal-Arcas, M

Proposal of a Nutritional Quality Index (NQI) to Evaluate the Nutritional Supplementation of Sportspeople

PLOS ONE, 2015;

FI:3,234; Q1

Martinez-Tome, M; Murcia, MA; Mariscal, M; Lorenzo, ML; Gomez-Murcia, V; Bibiloni, M; Jimenez-Monreal, AM

Evaluation of antioxidant activity and nutritional composition of flavoured dehydrated soups packaged in different formats. Reducing the sodium content

JOURNAL OF FOOD SCIENCE AND TECHNOLOGY-MYSORE, 2015;

FI:2,203; Q1

Jimenez, B; Sanchez-Ortiz, A; Lorenzo, ML; Rivas, A

Effect of Agronomical Practices on the Nutritional Quality of Virgin Olive Oil at Different Ripening Stages

JOURNAL OF THE AMERICAN OIL CHEMISTS SOCIETY, 2015;

FI:1,541; Q2

Monteagudo, C; Dijkstra, SC; Visser, M

Self-perception of body weight status in older Dutch adults

JOURNAL OF NUTRITION HEALTH & AGING, 2015;

FI:2,996; Q2

Fármacos y disruptores endocrinos en el medioambiente. Comportamiento y destino comocontaminantes

Financiador: UNIVERSIDAD DE GRANADA

Número de expediente: C-EXP-047-UGR23

Tiempo de ejecución: 01/01/2024 - 31/12/2026

IP: ALBERTO ZAFRA GOMEZ

Estudio de la exposición postnatal a disruptores endocrinos en obesidad y neurodesarrollo infantil

Financiador: UNIVERSIDAD DE GRANADA

Número de expediente: PPJIB2023-026

Tiempo de ejecución: 01/01/2024 - 31/12/2024

IP: VIVIANA RAMIREZ LOPEZ

Efecto de la exposición a disruptores endocrinos en la obesidad y neurodesarrollo. Papel de la variabilidad genética y la microbiota (NEUROBESS)

Financiador: INSTITUTO DE SALUD CARLOS III - FEDER

Número de expediente: PI23/01359

Tiempo de ejecución: 01/01/2024 - 31/12/2026

IP: ANA MARIA RIVAS VELASCO

Herramienta de ayuda a la decisión en la selección de tratamiento de pacientes de cáncer de próstata.

Financiador: INSTITUTO DE SALUD CARLOS III - FEDER

Número de expediente: PMPTA23/00025

Tiempo de ejecución: 01/01/2024 - 31/12/2025

IP: MARIA JESUS ALVAREZ CUBERO

EFECTO DE LA EXPOSICIÓN POSTNATAL A DISRUPTORES ENDOCRINOS EN LOS TRASTORNOS DEL NEURODESARROLLO Y LA OBESIDAD INFANTIL. PAPEL DE LA VARIABILIDAD GENÉTICA

Financiador: FUNDACIÓN PÚBLICA PARA LA INVESTIGACIÓN BIOSANITARIA DE ANDALUCIA ORIENTAL ALEJANDRO OTERO (FIBAO)

Número de expediente: INTRAIBS-2021-02

Tiempo de ejecución: 05/02/2022 - 04/02/2023

IP: MARIA VEGA ALMAZAN FERNANDEZ DE BOBADILLA

Caracterización profunda de la serie blanca de pacientes con patología COVID-19 para su cribado por agresividad.

Financiador: CONSEJERÍA DE SALUD Y FAMILIAS

Número de expediente: PECOVID-0006-2020

Tiempo de ejecución: 28/10/2021 - 27/10/2023

IP: SILVIA MARTINEZ DIZ

INFLUENCE OF ENDOCRINE DISRUPTERS CHEMICALS ON GUT MICROBIOTE: A MISSED LINK IN CHILDHOOD OBESITY (ENDOMICROMICS)

Financiador: INSTITUTO DE SALUD CARLOS III - FEDER

Número de expediente: PI20/01278

Tiempo de ejecución: 01/01/2021 - 31/12/2023

IP: ANA MARIA RIVAS VELASCO

ESTUDIO DE LA EXPOSICION A SUSTITUTOS DEL BESFENOS A DISCRUPTORES ENDOCRINOS EN NIÑOS EN EDAD ESCOLAR Y SU RELACION CON LA OBESIDAD

Financiador: FUNDACION MAPFRE

Número de expediente: MAPFRE2018

Tiempo de ejecución: 23/01/2019 - 22/01/2020

IP: ANA MARIA RIVAS VELASCO

Estudio de la exposición a analogos del Bisfenol A con actividad hormonal en niños en edad escolar y su relación con la obesidad.

Financiador: INSTITUTO DE SALUD CARLOS III - FEDER

Número de expediente: PI17/01758

Tiempo de ejecución: 01/01/2018 - 31/12/2020

IP: ANA MARIA RIVAS VELASCO

EFECTO DE LA EXPOSICIÓN ALIMENTARIA A DISRUPTORES ENDOCRINOS EN LA MICROBIOTA INTESTINAL EN NIÑOS. PAPEL EN EL FENOTIPO OBESOGENICO

Financiador: CONSEJERÍA DE SALUD Y FAMILIAS

Número de expediente: PE-0250-2019

Tiempo de ejecución: 23/12/2019 - 22/12/2023

IP: ANA MARIA RIVAS VELASCO

Estudio piloto multicéntrico, aleatorizado, doble-ciego de grupos paralelos para evaluar el efecto del consumo de una combinación de cepas probióticas y de una combinación de extractos de plantas y una cepa probiótica sobre la producción y la composición

Financiador: BIOSEARCH, S.A.

Tipo de prueba: INV. CLINICA PRODUCTO SANITARIO COM.

Tiempo de ejecución: 14/12/2020 - 28/02/2021

IP: MARIA VEGA ALMAZAN FERNANDEZ DE BOBADILLA